2020-10-01 12:45:41

Introduction

  • The following is a brief overview of several projects I have been involved with on COVID-19.
  • Some are research focused, some are more operational.
  • I’ll describe each project very briefly. I’ll pause after each one so we can discuss.
  • Slides here: https://www.andreashandel.com/talk/

Considering indirect benefits is critical when evaluating SARS-CoV-2 vaccine candidates

Motivation

  • As COVID vaccines become (hopefully soon) available, figuring out how to roll them out in the most efficient way is not easy.
  • Simulation models can help guide decisions regarding vaccination campaigns.

Methods

  • Build simulation models that include vaccination, explore the impact of different vaccination strategies for currently hypothetical, later real vaccine candidates.

Results

Acknowledgments and More Information

If long-term suppression is not possible, how do we minimize mortality for COVID-19 and other emerging infectious disease outbreaks?

Motivation

  • In some countries/areas, COVID-19 suppression might not be achievable.
  • If we have to contend with spread, how do we ensure that the lowest number of people die?
  • We explored a simple model with age-structured risk of mortality to explain conceptually how best to implement interventions.

Model

Results

S1 - no interventions. S2 - strong interventions. S3-S5, interventions mainly targeting children/adults/elderly.

Acknowledgments and More Information

Assessing the impact of a symptom-based mass screening and testing intervention during a novel infectious disease outbreak: The case of COVID-19

Motivation

  • China and other countries used a mass screening and testing intervention (MSTI) approach.
  • If MSTI overloads the healthcare system, and especially if conditions in testing facilities are not safe, this could lead to additional transmission.
  • What are the benefits and risks of MSTI and under what conditions is it a good strategy?

Model

Results